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Oncology FAQ

Patients most often ask a medical oncologist how long treatment will take, how to cope with side effects, what to eat, whether they can keep working, when a genomic test is needed and how to arrange a second opinion or an appointment from abroad. This oncology FAQ gives 24 short, referenced answers. They are general information; decisions about your own treatment are made at a consultation.

The questions are grouped into five topics. Each answer refers in square brackets to the guideline or patient resource it is based on; the full list is at the end of the page. Questions specific to one cancer or one treatment are answered on the relevant pages, so this page gives the short answer and a link rather than repeating them. Treatment is chosen by the physician on the basis of stage, pathology and molecular findings for each patient.

Please note: The answers on this page are general information and do not replace a consultation. In an emergency such as fever, breathlessness or bleeding, go to the nearest emergency department or call 112 in Türkiye.

Diagnosis and Staging

At the time of diagnosis, patients most often ask whether cancer can spread to others, whether it runs in families and what the numbers on their reports mean. The answers below are general; your own reports are interpreted at the consultation.

Is cancer contagious?

No. Cancer does not pass from one person to another; cancer cells from another person are destroyed by a healthy immune system, and kissing, sharing food or sexual contact do not transmit it. What can be transmitted are certain viruses, such as HPV and hepatitis B, which raise the risk of some cancers over many years. Vaccines and screening programmes exist for these infections [3][5].

Is cancer hereditary?

Most cancers are not inherited. In roughly five to ten percent of cases an inherited gene change plays a part [4][5]. The same cancer occurring at a young age or in several members of one family is a reason to assess hereditary risk. The assessment uses a blood test together with genetic counselling; details are on the hereditary cancer risk assessment page.

Does a raised tumour marker mean I have cancer?

No. A raised tumour marker on its own does not diagnose cancer. Markers such as CEA, CA 125 and CA 19-9 can also rise with inflammation, liver disease, smoking and benign cysts [4][5]. In practice these tests are used more to follow treatment response and detect recurrence than to make a diagnosis. A raised value is interpreted by the physician together with imaging and, where needed, a biopsy.

What does the SUV value on a PET report mean?

SUV is a number that describes how much of the sugar-based tracer an area has taken up on a PET scan; a higher value means the cells there are using sugar faster [5]. Cancer cells often show high uptake, but infection, inflammation and healing tissue can too. SUV does not diagnose cancer on its own, and different scanners give different values, so the number is read alongside the clinical picture and the other tests.

Can stage 4 cancer be treated?

Yes. Stage 4 (metastatic) cancer can be treated; the aims are to keep the disease under control, extend life and relieve symptoms [1][2]. In some cancers, targeted therapy or immunotherapy can keep the disease controlled for long periods. The outcome depends on the type of cancer, its molecular findings and the patient's general condition, and it varies from person to person. The aim of treatment is discussed openly at the first consultation.

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Treatment and Side Effects

During treatment, the most frequent questions concern how long it will last, working life and side effects. Treatment is chosen by the physician according to stage, pathology and molecular findings; managing side effects is part of the treatment itself.

How long does cancer treatment take?

It depends on the type of cancer, the stage and the aim of treatment. Preventive chemotherapy after surgery usually lasts three to six months; hormonal therapy for breast cancer five to ten years; in metastatic disease, treatment continues for as long as it is working [1][2]. Immunotherapy is planned for up to two years in many cancers. Details are on the chemotherapy and immunotherapy pages; your own plan is set at the consultation.

Can I work during chemotherapy?

Many patients continue to work during treatment; whether this is possible depends on the nature of the job, the treatment schedule and side effects [4]. Tiredness and nausea are usually most noticeable in the first few days after each cycle, and time off or flexible hours can be planned for those days. Jobs with a high risk of infection need extra precautions. Work and any sick-leave documentation are discussed with the physician around the treatment calendar.

What should I do if I get a fever during chemotherapy?

A temperature of 38 °C or higher during chemotherapy is an emergency: go to a hospital emergency department without waiting, or call 112 in Türkiye [7]. Chemotherapy can temporarily lower the white blood cells, and an infection can become serious within hours. Tell the emergency team that you are on chemotherapy and give the date of your last cycle; a blood count will be taken and intravenous antibiotics started if needed. Taking a fever tablet and waiting at home is not advised.

Can I have vaccines during treatment?

Non-live vaccines, such as those against influenza, pneumococcal disease and COVID-19, can be given during chemotherapy and immunotherapy and are recommended; the timing is chosen with the physician around the treatment calendar [1][4]. Live vaccines, such as measles, chickenpox and yellow fever, are not given while the immune system is suppressed. Vaccinating the people you live with also protects you. The vaccine plan is reviewed with the physician at the start of each treatment.

Can I have dental treatment during chemotherapy?

Procedures such as tooth extraction should be done before treatment starts where possible, because bleeding and infection are more likely on the days when blood counts are low during chemotherapy [4]. Non-urgent dental work is planned between cycles, when the blood count allows and with the physician's agreement. Patients taking bone-strengthening drugs (bisphosphonates or denosumab) need a separate assessment before any extraction. Always tell the dentist that you are having cancer treatment.

Do alternative treatments work?

There is no proven alternative treatment for cancer. So-called cancer vaccines sold outside clinical trials, high-dose vitamins, herbal regimens and similar products are not listed as treatment options in any guideline [1][2][4]. They can delay standard treatment or interact with cancer drugs and cause harm. Complementary approaches such as exercise and relaxation techniques can be used to ease side effects with the physician's knowledge. Tell the physician about every product you use.

Diet and Daily Life

Food, herbal products and travel are the everyday questions patients raise most often. The answers below draw on ESMO and NCCN patient resources; an individual eating plan is made with a dietitian. Questions about immunotherapy side effects are answered on the immunotherapy page.

How should I eat during treatment?

The aim during treatment is to avoid losing weight and muscle. A balanced diet with enough protein (meat, fish, eggs, pulses, dairy), vegetables, fruit and whole grains is recommended [8][3]. On days with nausea, small frequent meals help; when appetite is poor, small high-protein portions are useful. There is no special cancer diet. If you lose a noticeable amount of weight, a dietitian assessment is requested.

Does sugar feed cancer?

No. Cutting out sugary food does not starve a tumour; every cell in the body uses glucose, and blood glucose is produced from healthy foods too [3][4]. Eating a lot of sugar can raise the risk of some cancers indirectly, through weight gain and diabetes, so moderation is sensible. Restricting the energy intake of a patient who is losing weight during treatment is harmful. Nutrition during treatment is planned around adequacy, not prohibitions.

Can I use herbal products during treatment?

Herbal products, black seed, turmeric supplements and high-dose vitamins can interact with chemotherapy and targeted therapy drugs; some change the level of the drug in the blood or put extra strain on the liver [3][4]. For this reason herbal products are not taken during treatment without asking the physician first. Tell the physician about every product you use, with the dose and how long you have taken it. Ordinary spices used in cooking are not a problem.

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Genomic and Genetic Tests

About tumour genomic tests and hereditary tests, patients ask when the test is requested, how the two kinds differ and what the result means. Full information is in the precision oncology section.

When is genomic testing requested?

Tumour genomic testing (comprehensive genomic profiling) is requested when a gene change that could change the choice of treatment is being looked for. The ESMO 2024 recommendations advise broad panel testing in advanced lung, colorectal, prostate, ovarian and bile duct cancers [9]. In early-stage disease, testing is usually limited to specific markers. The decision is made by the physician according to tumour type and stage; details are on the comprehensive genomic profiling page.

What is the difference between tumour testing and hereditary testing?

Tumour testing looks for changes in the tumour tissue itself (somatic changes) and is used to choose treatment; hereditary testing is done on a blood sample and looks for changes carried from birth (germline changes) [9][1]. Somatic changes are not passed on to children; germline changes concern family members as well. If a tumour test shows a finding that might be inherited, a confirmatory blood test and genetic counselling are recommended.

What does a variant of uncertain significance mean?

A variant of uncertain significance (VUS) is a change found in a gene whose link to disease is not yet known [9]. It is not used to estimate cancer risk or to decide treatment, and most VUS findings are reclassified as harmless over time. Relatives are not offered testing for a VUS. The finding is reviewed at the molecular tumour board against evidence databases such as ClinVar and OncoKB, and it may be reinterpreted in future.

Appointments and Travel

Second opinions, appointments from abroad, follow-up and the practical side of travelling for treatment are explained step by step in the patient guide and on the international patients page. The short answers are below.

How do I get a second opinion?

A second opinion is a review of your existing diagnosis and treatment plan by another medical oncologist. It is your right, and it does not mean rejecting your first doctor's plan [1][4]. Send your pathology report, imaging reports and treatment summary by WhatsApp or email; they are reviewed before the consultation, which can be held in person or remotely. The plan is compared with current guidelines and you receive a written summary. The process is described on the second opinion page.

How do I book an appointment from abroad?

Write in English to +90 533 398 50 77 on WhatsApp or to drpetekkaya@gmail.com, giving your name, diagnosis and whether you want a first assessment or a second opinion, and attach your reports. They are reviewed remotely before any decision to travel, and a written opinion is sent. If a visit to Izmir is appropriate, the appointment is planned around your travel. Replies are sent during working hours, Turkish time (UTC+3). Details are on the international patients page.

How often are follow-ups after treatment?

The frequency of follow-up depends on the cancer type and stage. For most cancers, guidelines recommend a visit every three to six months for the first two to three years, then every six to twelve months [1][2]. A visit includes an examination and blood tests, with imaging when needed; imaging is not required at every visit. After five years, visits become less frequent. If a new symptom appears, contact the physician without waiting for the next visit.

Can I get a letter for a medical visa?

Yes. Once your records have been reviewed and a consultation or treatment in Izmir has been agreed, the hospital can issue a letter confirming the appointment for your visa application. Whether you need a visa, and which type, depends on your nationality; many nationalities can apply for an e-Visa online, and others apply through a Turkish consulate. Check the current rules on the official e-Visa and Ministry of Foreign Affairs websites before travelling [10][11].

Is my travel insurance valid for treatment abroad?

Usually not. Standard travel insurance covers unexpected illness on a trip; it generally excludes treatment that was planned before departure and often excludes complications of a known cancer diagnosis [3]. Read the policy wording and ask the insurer in writing before you travel. Planned treatment in Türkiye is normally paid for by the patient directly or through a private health plan that has agreed to it in advance; the hospital's international office can explain what documentation it needs.

Can I bring my own medication through customs?

Prescription medicines for personal use can generally be brought into Türkiye in quantities that match the length of your stay, in their original packaging and with a copy of the prescription or a doctor's letter in English. Controlled medicines, such as strong painkillers, need particular care and may require additional documentation. Confirm the current rules with Turkish customs and with your airline before travelling. Bring a full list of your medicines to the consultation.

What if I need emergency care while in Izmir?

Go to the nearest hospital emergency department or call 112, the national emergency number in Türkiye, which is free from any phone. If you are receiving treatment at Egepol Hastanesi, its emergency department is open around the clock and has access to your treatment record. Carry your treatment summary and medicine list with you. Tell the emergency team that you are having cancer treatment and the date of your last cycle. WhatsApp and email are not for emergencies.

Sources

  1. National Comprehensive Cancer Network. NCCN Guidelines for Patients. Link
  2. European Society for Medical Oncology. ESMO Patient Guides. Link
  3. Cancer Research UK. About cancer: coping, diet, travel and treatment side effects. Link
  4. National Cancer Institute. Understanding cancer; diagnosis and staging; tumour markers. Link
  5. World Health Organization. Cancer fact sheet. Link
  6. Haanen J, et al. Management of toxicities from immunotherapy: ESMO Clinical Practice Guideline. Annals of Oncology, 2022. DOI
  7. Klastersky J, et al. Management of febrile neutropaenia: ESMO Clinical Practice Guidelines. Annals of Oncology, 2016. DOI
  8. Arends J, et al. Cancer cachexia in adult patients: ESMO Clinical Practice Guidelines. ESMO Open, 2021. DOI
  9. Mosele MF, et al. Recommendations for the use of next-generation sequencing (NGS) for patients with advanced cancer in 2024: a report from the ESMO Precision Medicine Working Group. Annals of Oncology, 2024. DOI
  10. Republic of Türkiye. Official electronic visa application system. Link
  11. Republic of Türkiye Ministry of Foreign Affairs. Visa information for foreigners. Link
  12. Republic of Türkiye Ministry of Health. 112 emergency health services. Link

Ask for an Assessment

You can contact the clinic on WhatsApp for an assessment: +90 533 398 50 77. Send your pathology and imaging reports with your message, or email them. Documents are reviewed before the consultation.